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1

SAE Technical Paper Series [SAE International SAE 2013 World Congress & Exhibition - (APR. 16, 2013)] SAE Technical Paper Series - Safety Analysis and Design for ISO 26262 - Model Based and Tool Supported

Born, Marc, Kath, Olaf, Holz, Eckhardt, Douglass, Bruce

Year:

2013

Language:

english

File:

PDF, 2.78 MB

english, 2013

2

Breath volatile organic compounds of lung transplant recipients with and without chronic lung allograft dysfunction

Küppers, Lucas, Holz, Olaf, Schuchardt, Sven, Gottlieb, Jens, Fuge, Jan, Greer, Mark, Hohlfeld, Jens

Journal:

Journal of Breath Research

Year:

2018

Language:

english

File:

PDF, 757 KB

english, 2018

3

Analysis of Human Breath by Millimeter-Wave/Terahertz Spectroscopy

Rothbart, Nick, Holz, Olaf, Koczulla, Rembert, Schmalz, Klaus, Hübers, Heinz-Wilhelm

Journal:

Year:

2019

Language:

english

File:

PDF, 3.21 MB

english, 2019

4

Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD

Carla Winkler, Elena N Atochina-Vasserman, Olaf Holz, Michael F Beers, Veit J Erpenbeck, Norbert Krug, Stefan Roepcke, Gereon Lauer, Martin Elmlinger, Jens M Hohlfeld

Journal:

Respiratory Research

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

5

Assessing airway inflammation in clinical practice – experience with spontaneous sputum analysis

Olaf Holz, Tanja Seiler, Andreas Karmeier, Jan Fraedrich, Helmut Leiner, Helgo Magnussen, Rudolf A Jörres, Lutz Welker

Journal:

BMC Pulmonary Medicine

Year:

2008

Language:

english

File:

PDF, 628 KB

english, 2008

6

Differences in basal and induced DNA single-strand breaks between human peripheral monocytes and lymphocytes

Olaf Holz, Rudolf Jörres, Anja Kästner, Helgo Magnussen

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1995

Language:

english

File:

PDF, 824 KB

english, 1995

7

In contrast to lung fibroblasts – no signs of senescence in skin fibroblasts of patients with emphysema

Kai-Christian Müller, Kirsten Paasch, Beke Feindt, Lutz Welker, Henrik Watz, Michael Weise, Ralph A. Schmid, Masaki Nakashima, Detlev Branscheid, Helgo Magnussen, Rudolf A. Jörres, Olaf Holz

Journal:

Experimental Gerontology

Year:

2008

Language:

english

File:

PDF, 305 KB

english, 2008

8

MAPK pathway mediates muscarinic receptor-induced human lung fibroblast proliferation

Sonja Matthiesen, Amit Bahulayan, Olaf Holz, Kurt Racké

Journal:

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

9

Effect of cetirizine dihydrochloride on the airway response to hypertonic saline aerosol in patients with chronic obstructive pulmonary disease (COPD)

Lars Grönke, Jens Schlenker, Olaf Holz, Theo A. Out, Helgo Magnussen, Rudolf A. Jörres

Journal:

Respiratory Medicine

Year:

2005

Language:

english

File:

PDF, 252 KB

english, 2005

10

Exhaled nitric oxide: Independent effects of atopy, smoking, respiratory tract infection, gender and height

Holger Dressel, Dorothea de la Motte, Jörg Reichert, Uta Ochmann, Raluca Petru, Peter Angerer, Olaf Holz, Dennis Nowak, Rudolf A. Jörres

Journal:

Respiratory Medicine

Year:

2008

Language:

english

File:

PDF, 232 KB

english, 2008

11

Aging and induced senescence as factors in the pathogenesis of lung emphysema

Stefan Karrasch, Olaf Holz, Rudolf A. Jörres

Journal:

Respiratory Medicine

Year:

2008

Language:

english

File:

PDF, 441 KB

english, 2008

12

Breath profiles by electronic nose correlate with systemic markers but not ozone response

Heike Biller, Olaf Holz, Horst Windt, Wolfgang Koch, Meike Müller, Rudolf A. Jörres, Norbert Krug, Jens M. Hohlfeld

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

13

Diagnostic outcome of two different CT-guided fine needle biopsy procedures

Lutz Welker, Reyhan Akkan, Olaf Holz, Holger Schultz, Helgo Magnussen

Journal:

Diagnostic Pathology

Year:

2007

Language:

english

File:

PDF, 352 KB

english, 2007

14

Spatial Interactions between Dendritic Cells and Sensory Nerves in Allergic Airway Inflammation

Veres, Tibor Z., Rochlitzer, Sabine, Shevchenko, Marina, Fuchs, Barbara, Prenzler, Frauke, Nassenstein, Christina, Fischer, Axel, Welker, Lutz, Holz, Olaf, Müller, Meike, Krug, Norbert, Braun, Armin

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.22 MB

english, 2007

15

Oncostatin M Modulates Fibroblast Function via Signal Transducers and Activators of Transcription Proteins–3

Nagahama, Kumi Yoneda, Togo, Shinsaku, Holz, Olaf, Magnussen, Helgo, Liu, Xiangde, Seyama, Kuniaki, Takahashi, Kazuhisa, Rennard, Stephen I.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 6.07 MB

english, 2013

16

Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development

Ole Janssen, Frank Schaumann, Olaf Holz, Bianca Lavae-Mokhtari…

Journal:

BMC Pulmonary Medicine

Year:

2013

Language:

english

File:

PDF, 442 KB

english, 2013

17

Localized Surface Plasmon Resonance Investigations of Photoswitching in Azobenzene-Functionalized Self-Assembled Monolayers on Au

Müller, Mathias, Jung, Ulrich, Gusak, Viktoria, Ulrich, Sandra, Holz, Michelle, Herges, Rainer, Langhammer, Christoph, Magnussen, Olaf

Journal:

Year:

2013

Language:

english

File:

PDF, 3.77 MB

english, 2013

18

Fast escape of hydrogen from gas cavities around corroding magnesium implants

Kuhlmann, Julia, Bartsch, Ivonne, Willbold, Elmar, Schuchardt, Sven, Holz, Olaf, Hort, Norbert, Höche, Daniel, Heineman, William R., Witte, Frank

Journal:

Acta Biomaterialia

Year:

2013

Language:

english

File:

PDF, 2.99 MB

english, 2013

19

Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics

Winkler, Carla, Witte, Lena, Moraw, Natali, Faulenbach, Conny, Müller, Meike, Holz, Olaf, Schaumann, Frank, Hohlfeld, Jens M

Journal:

Year:

2014

Language:

english

File:

PDF, 404 KB

english, 2014

20

Isolated Bronchi of Patients with COPD Show Decreased Histamine Responsiveness Compared to Smokers with Normal Lung Function

Taube, Christian, Einhaus, Martin, Welker, Lutz, Holz, Olaf, Branscheid, Detlev, Magnussen, Helgo, Jörres, Rudolf A.

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

21

Multi-analyte profiling of inflammatory mediators in COPD sputum – The effects of processing

Pedersen, Frauke, Holz, Olaf, Lauer, Gereon, Quintini, Gianluca, Kiwull-Schöne, Heidrun, Kirsten, Anne-Marie, Magnussen, Helgo, Rabe, Klaus F., Goldmann, Torsten, Watz, Henrik

Journal:

Year:

2015

Language:

english

File:

PDF, 274 KB

english, 2015

22

Potential prognostic value of biomarkers in lavage, sputum and serum in a five year clinical follow-up of smokers with and without COPD

Holz, Olaf, Waschki, Benjamin, Roepcke, Stefan, Watz, Henrik, Lauer, Gereon, Faulenbach, Cornelia, Hohlfeld, Jens M

Journal:

BMC Pulmonary Medicine

Year:

2014

Language:

english

File:

PDF, 454 KB

english, 2014

23

Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma

Pedersen, Frauke, Holz, Olaf, Kanniess, Frank, Zielen, Stefan, Schulze, Johannes, Gillissen, Adrian, von Berg, Andrea, Berdel, Dietrich, Beier, Jutta, Beeh, Kai, Schnoor, Maike, Magnussen, Helgo

Journal:

BMC Research Notes

Year:

2014

Language:

english

File:

PDF, 722 KB

english, 2014

24

Disease Progression and Changes in Physical Activity in Patients with Chronic Obstructive Pulmonary Disease

Waschki, Benjamin, Kirsten, Anne M., Holz, Olaf, Mueller, Kai-Christian, Schaper, Miriam, Sack, Anna-Lena, Meyer, Thorsten, Rabe, Klaus F., Magnussen, Helgo, Watz, Henrik

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

25

Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients

Pedersen, Frauke, Marwitz, Sebastian, Holz, Olaf, Kirsten, Anne, Bahmer, Thomas, Waschki, Benjamin, Magnussen, Helgo, Rabe, Klaus F., Goldmann, Torsten, Uddin, Mohib, Watz, Henrik

Journal:

Respiratory Medicine

Year:

2015

Language:

english

File:

PDF, 587 KB

english, 2015

26

Lung Fibroblast Repair Functions in Patients with Chronic Obstructive Pulmonary Disease Are Altered by Multiple Mechanisms

Togo, Shinsaku, Holz, Olaf, Liu, Xiangde, Sugiura, Hisatoshi, Kamio, Koichiro, Wang, Xiangqi, Kawasaki, Shin, Ahn, Youngsoo, Fredriksson, Karin, Skold, C. Magnus, Mueller, Kai Christian, Branscheid, D

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2008

Language:

english

File:

PDF, 780 KB

english, 2008

27

Reduced miR-146a Increases Prostaglandin E 2 in Chronic Obstructive Pulmonary Disease Fibroblasts

Sato, Tadashi, Liu, Xiangde, Nelson, Amy, Nakanishi, Masanori, Kanaji, Nobuhiro, Wang, Xingqi, Kim, Miok, Li, Yingji, Sun, Jianhong, Michalski, Joel, Patil, Amol, Basma, Hesham, Holz, Olaf, Magnussen,

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

28

Airway Response to Inhaled Hypertonic Saline in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease

TAUBE, CHRISTIAN, HOLZ, OLAF, MÜCKE, MARION, JÖRRES, RUDOLF A., MAGNUSSEN, HELGO

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2001

Language:

english

File:

PDF, 253 KB

english, 2001

29

The Effect of Repeated Ozone Exposures on Inflammatory Markers in Bronchoalveolar Lavage Fluid and Mucosal Biopsies

JÖRRES, RUDOLF A., HOLZ, OLAF, ZACHGO, WOLFGANG, TIMM, PETRA, KOSCHYK, SILKE, MÜLLER, BERND, GRIMMINGER, FRIEDRICH, SEEGER, WERNER, KELLY, FRANK J., DUNSTER, CHRISTINE, FRISCHER, THOMAS, LUBEC, GERD,

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2000

Language:

english

File:

PDF, 84 KB

english, 2000

30

Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model - a clinical trial

Holz, Olaf, Biller, H., Mueller, M., Kane, K., Rosano, M., Hanrahan, J., Hava, D. L., Hohlfeld, J. M.

Journal:

BMC Pharmacology and Toxicology

Year:

2015

Language:

english

File:

PDF, 699 KB

english, 2015

31

Ozone-induced Airway Inflammatory Changes Differ between Individuals and Are Reproducible

HOLZ, OLAF, JÖRRES, RUDOLF A., TIMM, PETRA, MÜCKE, MARION, RICHTER, KAI, KOSCHYK, SILKE, MAGNUSSEN, HELGO

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

1999

Language:

english

File:

PDF, 142 KB

english, 1999

32

Association of Tumor Necrosis Factor-α Polymorphisms and Ozone-induced Change in Lung Function

Yang, Ian A., Holz, Olaf, Jörres, Rudolf A., Magnussen, Helgo, Barton, Sheila J., Rodríguez, Santiago, Cakebread, Julie A., Holloway, John W., Holgate, Stephen T.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 83 KB

english, 2005

33

Physical Activity Is the Strongest Predictor of All-Cause Mortality in Patients With COPD

Waschki, Benjamin, Kirsten, Anne, Holz, Olaf, Müller, Kai-Christian, Meyer, Thorsten, Watz, Henrik, Magnussen, Helgo

Journal:

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

34

The Metabolic Syndrome in Patients With Chronic Bronchitis and COPD

Watz, Henrik, Waschki, Benjamin, Kirsten, Anne, Müller, Kai-Christian, Kretschmar, Gunther, Meyer, Thorsten, Holz, Olaf, Magnussen, Helgo

Journal:

Year:

2009

Language:

english

File:

PDF, 140 KB

english, 2009

35

Metabolic Syndrome and Impaired Lung Function: Response

Watz, Henrik, Waschki, Benjamin, Kirsten, Anne, Müller, Kai-Christian, Kretschmar, Gunther, Meyer, Thorsten, Holz, Olaf, Magnussen, Helgo

Journal:

Year:

2010

Language:

english

File:

PDF, 87 KB

english, 2010

36

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C70. REPAIR AND REGENERATION: STEM CELL FUNCTIONS AND APPLICATIONS - Generation Of IPS-Like Cells From COPD Lung Fibroblasts

Basma, Hesham, Gunji, Yoko, Liu, Xiangde, Nelson, Amy, Farid, Maha, Iwasawa, Shunichiro, Ikari, Jun, Wang, Xingqi, Holz, Olaf, Mueller, Kai-Christian, Magnussen, Helgo, Rabe, Klaus, Rennard, Stephen I

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

37

Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development

Holz, Olaf, Tal-Singer, Ruth, Kanniess, Frank, Simpson, Kathy J., Gibson, Anthony, Vessey, Rupert S. J., Janicki, Stanislawa, Magnussen, Helgo, Jörres, Rudolf A., Richter, Kai

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 113 KB

english, 2005

38

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C38. ADVANCES IN ASTHMA AND COPD SCREENING AND MONITORING - Low-Dose Endotoxin Inhalation In Healthy Volunteers: A Challenge Model For Early Clinical Drug Development Of Novel Anti-Inflammatory Compounds

Schaumann, Frank, Holz, Olaf, Janben, Ole, Lavae-Mokhtari, Bianca, Witte, Lena, Biller, Heike, Krug, Norbert, Hohlfeld, Jens M.

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

39

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] D13. BIOMARKERS IN THE CLINIC: FROM IMAGING TO MOLECULAR PROFILING - Analysis Of Volatile Organic Compounds In Exhaled Air With A Novel Compact Mass Spectrometer (Smart-Nose®)

Holz, Olaf, Zesiger, Thierry, Lavae-Mokhtari, Bianca, Schuchardt, Sven, Krug, Norbert, Hohlfeld, Jens M.

Year:

2011

Language:

english

File:

PDF, 18 KB

english, 2011

40

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] D63. SIGNAL TRANSDUCTION: MEMBRANE RECEPTORS AND INTRACELLULAR PATHWAYS - PGE2 Stimulates Human Lung Fibroblast IL-8 Production Through The EP2 Receptor

Nakanishi, Masanori, Holz, Olaf, Sato, Tadashi, Farid, Maha, Nelson, Amy J., Michalski, Joel, Kanaji, Nobuhiro, Wang, Xingqi, Basma, Hesham, Liu, Xiangde, Togo, Shinsaku, Toews, Myron L., Mueller, Kai

Year:

2010

Language:

english

File:

PDF, 18 KB

english, 2010

41

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] B34. INFLAMMATORY MECHANISMS IN ASTHMA - Depletion Of Neutrophils From Induced Sputum Using A Novel Bead And Sieve-Separation System

Holz, Olaf, Schaumann, Frank, Janben, Ole, Lavae-Mokhtari, Bianca, Witte, Lena, Krug, Norbert, Heinrich, J M., Hohlfeld, Jens M.

Year:

2012

Language:

english

File:

PDF, 17 KB

english, 2012

42

Airway and systemic inflammatory responses to ultrafine carbon black particles and ozone in older healthy subjects

Holz, Olaf, Heusser, Karsten, Müller, Meike, Windt, Horst, Schwarz, Katharina, Schindler, Christoph, Tank, Jens, Hohlfeld, Jens M., Jordan, Jens

Journal:

Journal of Toxicology and Environmental Health Part A

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

43

Repeatability of and Relationship between Potential COPD Biomarkers in Bronchoalveolar Lavage, Bronchial Biopsies, Serum, and Induced Sputum

Röpcke, Stefan, Holz, Olaf, Lauer, Gereon, Müller, Meike, Rittinghausen, Susanne, Ernst, Peter, Lahu, Gezim, Elmlinger, Martin, Krug, Norbert, Hohlfeld, Jens M., Hartl, Dominik

Journal:

Year:

2012

Language:

english

File:

PDF, 406 KB

english, 2012

44

Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function

Waschki, Benjamin, Watz, Henrik, Holz, Olaf, Magnussen, Helgo, Olejnicka, Beata, Welte, Tobias, Rabe, Klaus F, Janciauskiene, Sabina

Journal:

International Journal of Chronic Obstructive Pulmonary Disease

Year:

2017

Language:

english

File:

PDF, 521 KB

english, 2017

45

Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD

Holz, Olaf, Roepcke, Stefan, Watz, Henrik, Tegtbur, Uwe, Lahu, Gezim, Hohlfeld, Jens

Journal:

International Journal of Chronic Obstructive Pulmonary Disease

Year:

2015

Language:

english

File:

PDF, 846 KB

english, 2015

46

Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans

Heusser, Karsten, Tank, Jens, Holz, Olaf, May, Marcus, Brinkmann, Julia, Engeli, Stefan, Diedrich, André, Framke, Theodor, Koch, Armin, Großhennig, Anika, Jan Danser, A. H., Sweep, Fred C. G. J., Schi

Journal:

Scientific Reports

Year:

2019

File:

PDF, 1.37 MB

2019

47

Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans

Heusser, Karsten, Tank, Jens, Holz, Olaf, May, Marcus, Brinkmann, Julia, Engeli, Stefan, Diedrich, André, Framke, Theodor, Koch, Armin, Großhennig, Anika, Jan Danser, A. H., Sweep, Fred C. G. J., Schi

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.37 MB

english, 2019

48

Noninvasive Monitoring of the Response of Human Lungs to Low‐Dose Lipopolysaccharide Inhalation Challenge Using MRI: A Feasibility Study

Kern, Agilo L., Biller, Heike, Klimeš, Filip, Voskrebenzev, Andreas, Gutberlet, Marcel, Renne, Julius, Müller, Meike, Holz, Olaf, Wacker, Frank, Hohlfeld, Jens M., Vogel‐Claussen, Jens

Journal:

Journal of Magnetic Resonance Imaging

Year:

2019

Language:

english

File:

PDF, 1.79 MB

english, 2019

49

Noninvasive Monitoring of the Response of Human Lungs to Low‐Dose Lipopolysaccharide Inhalation Challenge Using MRI: A Feasibility Study

Kern, Agilo L., Biller, Heike, Klimeš, Filip, Voskrebenzev, Andreas, Gutberlet, Marcel, Renne, Julius, Müller, Meike, Holz, Olaf, Wacker, Frank, Hohlfeld, Jens M., Vogel‐Claussen, Jens

Journal:

Journal of Magnetic Resonance Imaging

Year:

2019

File:

PDF, 1.79 MB

2019

50

Detecting vision loss in intermediate age-related macular degeneration: A comparison of visual function tests

Pondorfer, Susanne G., Heinemann, Manuel, Wintergerst, Maximilian W. M., Pfau, Maximilian, StrÃ¶mer, Annika L., Holz, Frank G., Finger, Robert P., StrauÃ, Olaf

Journal:

Year:

2020

File:

PDF, 858 KB

2020